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I en kommentar fra en pasientrepresentant i komitéen, Lucy Ryan, understrekes det at denne retningslinjen kan bidra til mer konsistens i behandlingen og støtten til personer med kronisk smerte.Adjuvanser brukes ikke som monoterapi ved kroniske smerter. Dette betyr at de ikke brukes alene som behandling for kroniske smerter.Man trenger vanligvis i